15 projects from Lyonbiopole members awarded in ANR 2023 generic call for projects

The 2023 generic call for projects is aimed at all scientific communities and all public and private players involved in French research. It is designed to enable researchers in different scientific fields to access co-financing for a large number of research themes, whether finalized or not, in addition to the recurrent funding allocated to them.

Of the 23 projects supported by Lyonbiopole, 15 have been awarded grants: a fine vintage once again this year.

ApicoLipidTraffic project led by Cyrille BOTTÉ from UGA’s Institute for Advanced Biosciences

• To elucidate how lipid transfers at membrane contact sites enable the propagation and survival of Toxoplasma gondii in its human host.

FLUOSICCA project led by Philippe GAIN of the Laboratoire de Biologie, Ingénierie et Imagerie pour l’Ophtalmologie at Université Jean Monet St Etienne

• Double fluorescent labeling of the ocular surface in dry syndrome

OptiMoCSI project led by Patrice ABRY of the Physics Laboratory, ENS Lyon

• Intertwined Monte Carlo optimization and sampling

PROLIC project led by Marie José STASIA of Grenoble-Alpes University Hospital and the UGA Structural Biology Institute

• Proof of concept of a proteoliposome-based local therapy for acute lung infections in patients with chronic septic granulomatosis

PneumoPEPS project led by Jean-Marie BOURHIS of Grenoble’s Institut de Biologie Structurale

• Nucleoprotein-Phosphoprotein interaction for the assembly of human respiratory syncytial virus nucleocapsids: deciphering mechanisms and developing antivirals

NEPTUNE project led by Allison BALLANDRAS-COLAS of Grenoble’s Institut de Biologie Structurale

• Nuclear export of Influenza virus RNA segments

DRAXCAN project led by Patrick MEHLEN of the Lyon Cancer Research Center

• Targeting Draxin in cancer

MP-ScaFF project led by Julien BARTHES of 3DEUS DYNAMICS

• Bone filling with multi-scale porosity and freedom of design

SAFROM project led by Louis-Marie BLOYET of Centre International de Recherche en Infectiologie

• Structure and function of the RNA synthesis machinery of mononegaviruses: vesicular stomatitis virus and Nipah virus

MILPATS project led by Xavier DÉLEN of LABORATOIRE CHARLES FABRY

• Mid-infrared laser platform for glycomics

GlowCryst project headed by Olivier MAURY of the ENS Lyon Chemistry Laboratory

• Lanthanide crystallophores, from protein crystal imaging to in vivo crystallization.

ESCRTpolyMID project led by Winfried WEISSENHORN of the Grenoble Institute of Structural Biology

• Polymerization of ESCRT-III and cleavage of the central cytokine body

CTRbyNMR project led by Guido PINTACUDA of the Centre de RMN à très hauts champs de Lyon (CNRS, UDL, ENS)

• Study of the structure and mechanism of the human copper ion transporter hCTR1 by ultrafast magic angle solid-state NMR

LACTIBIOTA project led by Marie-Caroline MICHALSKI of Cardiovascular, Metabolism, Diabetes, Diabetology and Nutrition (INSERM, INRAE, UDL, INSA)

• Dairy bacteria and lipids as a sustainable strategy for a health-promoting human gut microbiota

ISAvi project led by Mathias FAURE of ED 340 BMIC – Integrative and Cellular Molecular Biology, University of Lyon

• The impact of selective autophagy on viral infection