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Promega Corporation is pleased to share a new publication in Nature Biomedical Engineering featuring a collaboration between Trish Hoang and Morten Seirup from Promega R&D and Dr. Ronit Mazor at the FDA. This paper highlights the application of a NanoLuc reporter in assessing the T Cell immune response to wild type and chimeric AAV capsid serotypes in vitro and in vivo. Through understanding how to rationally evade preexisting AAV immunogenic responses, these researchers hope to make AAV gene therapy safer and available to a wider range of patient populations. 



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