Published in Lancet Oncology.
Paris, France, May 3, 2023 – Carthera, a French company that designs and develops SonoCloud, an innovative ultrasound-based medical device to treat a wide range of brain diseases, announces today the publication in Lancet Oncology of results from a phase I clinical trial carried out by scientists at Northwestern University Feinberg School of Medicine (Chicago, Illinois, US). They used the SonoCloud-9® implantable ultrasound device to repeatedly open the Blood-Brain Barrier (BBB) to deliver chemotherapy in patients with recurrent glioblastoma. The results show the treatment was safe and well-tolerated, with some patients receiving up to six cycles of treatment.