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SAPPIENS is a clinical-stage biotech developing first-in-class disease-modifying therapies for Parkinson’s disease (PD) and Amyotrophic lateral sclerosis (ALS), two severe neurodegenerative diseases with significant unmet medical needs. ALS remains an orphan disease and is often associated with a life expectancy of only 3–5 years following symptom onset. Our lead candidate, CXS003, is an innovative, patented drug-candidate designed to simultaneously modulate 3 key drivers of neurodegeneration: oxidative stress, neuro-inflammation, and mitochondrial dysfunction. SAPPIENS is built on an experienced founding team combining strategic, scientific, and clinical expertise, along with a strong track record in company creation and development, supported by a network of leading experts in both diseases.

 

Application market: Neurology & Mental Health Disorders

Type of activity: Therapeutics, Pharma or Biotech

Technologies: Small Molecules

Created on oct. 2nd, 2025 - 4 employees

 

Address

4 Place Loiseau d'Entraigues 37000 Tours

 

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