Cancer Research Center of Lyon
Member of Lyonbiopole
The Cancer Research Center of Lyon (CRCL) is led by A. Puisieux (the directing deputies being P. Mehlen and C. Dumontet) and is dedicated to basic research in oncology. The CRCL is affiliated with the Inserm, the CNRS, the Université Claude Bernard Lyon 1, the Centre Léon Bérard, and with the Hospices Civils de Lyon as a clinical partner. The aim of the CRCL is to extend its international recognition and the attractiveness of its research cluster, to facilitate the transfer of knowledge from fundamental cancer research to clinical applications, and to develop teaching and training in oncology. This Center, created in 2011, comprises 22 research teams for 450 members, including 140 permanent scientists, organized in 3 departments.
Unit code: UMR INSERM 1052 / CNRS 5286 / Centre Léon Bérard
Affiliation organization: CNRS, INSERM, UCBL (Université Claude Bernard Lyon 1)
Teams
Inflammasome and cancer
Inflammasomes, Cancer
Contact: Virginie Petrilli - virginie.petrilli@lyon.unicancer.fr
Transcriptome diversity in stem cells
Transcriptome, Stem cell
Contact: Mathieu Gabut - mathieu.gabut@inserm.fr
Epigenetics and epigenomics of hepatocellular carcinoma
Epigenetics, Epigenomics, HCC
Contact: Massimo Levrero - massimo.levrero@inserm.fr
BMP, tumoral niche and resistance
Bone Morphogenetic Protein, Stem Cell, Tumor Niche
Contact: Véronique Maguer-Satta - veronique.maguer-satta@lyon.unicancer.fr
TGF-beta and immune evasion
Immunity, TGF-beta
Contact: Julien Marie - julien.marie@inserm.fr
Cancer cell death
Apoptose, Mitochondries, caspases
Contact: Gabriel Ichim - gabriel.ichim@lyon.unicancer.fr
Cellular reprogramming and oncogenesis
Oncogenesis, Reprogramming
Contact: Fabrice Lavial - fabrice.lavial@lyon.unicancer.fr
EMT and cancer cell plasticity
EMT, Plasticity
Contact: Alain Puisieux - alain.puisieux@lyon.unicancer.fr
Anticancer antibodies
Antibodies, Cancer
Contact: Charles Dumontet - charles.dumontet@chu-lyon.fr
Dependence receptors, cancer and development
Dependence, Receptors
Contact: Patrick Mehlen - patrick.mehlen@lyon.unicancer.fr
Development, cancer and stem cells
Stem cells, Cancer, Colorectal
Contact: Michelina Plateroti - michelina.plateroti@univ-lyon1.fr
Nuclear domains and pathologies
Ribosomes, Cancer development
Contact: Jean-Jacques Diaz - jean-jacques.diaz@lyon.unicancer.fr
Pathogenesis of hepatitis B and C infections
Hepatitis, Virus, Liver cancer
Contact: Fabien Zoulim - fabien.zoulim@inserm.fr
Senescence escape mechanisms
Senescence
Contact: David Bernard - david.bernard@lyon.unicancer.fr
Targeting of the tumor and its immune environment
Immunity, Tumor
Contact: Caux Christophe Blay Jean-Yves, - jean-yves.blay@lyon.unicancer.fr, christophe.caux@lyon.unicancer.fr
Steroid signaling and breast tumor
Breast cancer, Estrogen
Contact: Muriel Le Romancer - muriel.leromancer@lyon.unicancer.fr
Hepatocarcinogenesis and viral infection
Carcinoma, Virus
Contact: Merle Philippe Chemin Isabelle - isabelle.chemin@inserm.fr, philippe.merle@inserm.fr
TGFbeta and pancreatic cancer
TGFbeta, Pancreas
Contact: Laurent Bartholin - laurent.bartholin@lyon.unicancer.fr
Innate immune signaling and oncogenesis
Oncogenesis, Innate immunity
Contact: Toufic Renno - toufic.renno@lyon.unicancer.fr
Signaling, metabolism and tumor progression
EMT, TGFbeta, Metabolism
Contact: Gillet Germain Rimokh Ruth, - ruth.rimokh@lyon.unicancer.fr, germain.gillet@lyon.unicancer.fr
Clinical and experimental models of lymphomagenesis
Lymphomagenesis, Lymphomas
Contact: Genestier Laurent Salles Gilles, - gilles.salles@chu-lyon.fr, laurent.genestier@inserm.fr
Epigenetics and cancer
Epigenetics
Contact: Peter Mulligan - peter.mulligan@lyon.unicancer.fr
Address
Centre Léon Bérard Cheney D
28 RUE LAENNEC 69008 LYON
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