Accueil   Diary - News   All news Transgene and Léon Bérard Cancer Center Announce Dosing of the First Patient in a Phase 1 Immunotherapy Clinical Trial Evaluating the Intra-Tumoral Co-Administration of Pexa-Vec plus Ipilimumab (Yervoy®)

Transgene and Léon Bérard Cancer Center Announce Dosing of the First Patient in a Phase 1 Immunotherapy Clinical Trial Evaluating the Intra-Tumoral Co-Administration of Pexa-Vec plus Ipilimumab (Yervoy®)

Transgene and Léon Bérard Cancer Center Announce Dosing of the First Patient in a Phase 1 Immunotherapy Clinical Trial Evaluating the Intra-Tumoral Co-Administration of Pexa-Vec plus Ipilimumab (Yervoy®) in Solid Cancers

 

 

 

 

Strasbourg, France, February 13, 2017, 6:00 p.m. CET - Transgene (Euronext Paris: TNG), a company focused on designing and developing viral-based immune-targeted therapies for the treatment of cancers and infectious diseases, today announces that the 1 st patient in the ISI-JX trial has been treated at the Léon Bérard Cancer Center in Lyon, France. ISI-JX is a Phase 1 clinical trial evaluating the intratumoral co-administration of Pexa-Vec in combination with ipilimumab in solid tumors (NCT02977156).

 

 

 

This investigator initiated trial promoted by the Leon Bérard Cancer Center will enroll patients with metastatic and/or locally advanced solid tumors. Pexa-Vec is a GM-CSF expressing vaccinia derived oncolytic virus co-developed by Transgene and SillaJen. Ipilimumab is a monoclonal antibody targeted against the immune checkpoint CTLA-4 and is currently approved for the treatment of melanoma (Yervoy®, Bristol-Myers Squibb).

 

 

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