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All news MaaT Pharma Announces Positive Topline Results from Phase 2 HERACLES Clinical Trial
Lyon, France, March 17, 2021 – MaaT Pharma announced today positive topline results from its Phase 2 clinical trial evaluating lead microbiome ecosystem therapy, MaaT013, in a high-risk patient population with grade III-IV steroid-refractory, gastrointestinal-predominant acute graft-versus-host disease (SR-GI-aGvHD). The study met its primary endpoint of clinical efficacy, demonstrating a combined 33.3% complete response rate (CR) or very good partial response rate (VGPR) at day 28. In addition, the overall response rate (ORR) was 38.1% at day 28 and the best overall response rate (BORR), i.e. the number of patients achieving a response at any point up to day 28, was 57.1%. MaaT013 also showed an acceptable safety profile.