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CarThera starts phase I/II trial

In collaboration with Northwestern University to test SonoCloud-9 in patients with recurrent glioblastoma



CarThera, a French company that designs and develops innovative ultrasound-based medical devices to treat brain disorders, today
announces the launch of a new phase I/II clinical trial (NCT04528680) in collaboration with Northwestern University in Chicago. The trial will recruit up to 39 patients with recurrent glioblastoma (GBM) to test the SonoCloud-9 device in combination with
Abraxane® - an albumin-bound formulation of paclitaxel. SonoCloud-9 is an implantable device with nine ultrasound emitters that are activated in conjunction with microbubbles to transiently open the blood-brain barrier. This allows the penetration of drugs such as Abraxane into the brain tissue. The first patient in this trial has been treated and further patient recruitment is now on-going.


Read the press release