ECLAIRE

Establishment of Cell Lines for vAccine vIral replication by somatic REprogramming

ECLAIRE est accrédité par Lyonbiopôle

Identity card

Global budget: 1310 k€

Public funding: 256 k€

Public funders: ANR, Agence Nationale de la Recherche

Call for projects: ANR

Year start: 2014

Completed project (2017-12)


Accredited by the French competitiveness cluster Lyonbiopôle


Strategic business area: Human Medicines, Animal Medicines

Application fields: Infectious diseases

Technological approaches / Keywords: Biologics, Cell model / Animal model

Stage of development at the beginning of the project: Basic research, Discovery

Abstract

At the scientific level, the project aims to use the strategy of somatic reprogramming to design and obtain new cell lines in an approach that is presently thought to be innovative as not yet reported for a viral vaccine production.


Objectives

The proposal aims to combine the somatic reprogramming with viral vaccine replication tests to generate and establish new cell lines that will be innovative cellular substrates.  


Innovative assets
Highlights
Perspectives

Innovative assets

Obtaining new vaccines, particularly safe and highly efficacious, is a major challenge for all stakeholders involved in the prevention against infectious diseases. The development of new innovative in vitro substrates contributes to this exigency, helps to secure the production and thus provides the necessary guarantees. The project is part of the need for ongoing development of new approaches, more controlled and safer, for the final benefits of human and animal health.

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