cMUT Applications for Therapy and Imaging in Onco-Nanosurgery

Identity card

Global budget: 3057 k€

Public funding: 1333 k€

Public funders: Fonds Unique Interministériel (FUI) – DGCIS/Oséo, Région Rhône-Alpes, Other (Conseil Régional Ile-de-France)

Call for projects: FUI (FUI AAP15)

Year start: 2013

Completed project

Accredited by the French competitiveness cluster S2E2 (Smart Electricity Cluster)

Co-accredited by the French competitiveness cluster Lyonbiopôle

Strategic business area: Human Medicines, Medical Technologies

Application fields: Neurology, Inflammatory diseases, Health & Environment, Oncology

Technological approaches / Keywords: Imaging (medical), Minimally Invasive Technologies

Stage of development at the beginning of the project: Preclinical development


  MUTATION is an industrial and clinical research project for the treatment of tumors, led by VERMON, a leader in medical ultrasound, Edap-TMS and CarThéra, developers of minimally invasive ultrasound therapy systems, and LabTAU, a laboratory which specializes in research on therapeutic ultrasound. Image-guided minimally-invasive therapeutic systems will be developed at preclinical and clinical levels. The medical devices developed will allow more effective and less expensive outpatient treatments.   


  The MUTATION project aims to study and transfer minimally-invasive image-guided ultrasound focal therapies at preclinical and clinical levels for the treatment of localized diseases. The project focuses primarily on oncological applications (brain, prostate, lung and liver). MUTATION’s products could also extend their field of applications to other medical domains involving various biological effects of ultrasound.   

Innovative assets
Actual results

Innovative assets

  The cMUT technology will be investigated in MUTATION for therapeutic ultrasound applications, and dual-mode cMUT ultrasound transducers will be developed for creating new generations of ultrasound medical devices capable of doing both focal therapy and high performance imaging. The technological leap possible by dual-mode cMUT ultrasound transducers will lead to new industrial-scale innovative projects in the field of health.