TEDAC

Therapy Enzymatic by Depletion of Amino acids to treat Cancers resistant to radio / chemotherapy

TEDAC est accrédité par Lyonbiopôle

Identity card

Global budget: 22 568 k€

Public funding: 10 690 k€

Public funders: Oséo / BPI France (except FUI)

Call for projects: ISI Oséo

Year start: 2011

Completed project


Accredited by the French competitiveness cluster Lyonbiopôle


Strategic business area: Human Medicines

Application fields: Oncology, Orphan diseases

Technological approaches / Keywords: Cell therapy / Regenerative Medicine, Drug delivery system

Stage of development at the beginning of the project: Preclinical development

Abstract

A high proportion of tumors is not or only a little responsive to radiotherapy and a significant proportion of tumors can have an intrinsic resistance or an acquired resistance to chemotherapy. The aim of the TEDAC project is to develop a new personalized medecine approach for the treatment of radio-chemoresistant cancer: an important unmet medical need. TEDAC responds to many challenges related to the management for this type of cancers that remain a high stake for clinician, patients and health autorities.  


Objectives

 The objective of this research project is to develop innovative enzymatic therapy targeting the depletion from tumor environment of  amino acids, that are essential for the tumor growth. TEDAC is a personalized medicine project with the co-development of diagnostic and monitoring test to secure and optimize the specific management of each patient treated.  


Innovative assets
Actual results
Perspectives

Innovative assets

Therapy Enzymatic by Depletion of Amino acids to treat Cancers resistant to radio / chemotherapy

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