HYPERBAR

High Isostatic Pressures Applicability to the Vaccine and Pharmaceutical Industry

HYPERBAR est accrédité par Lyonbiopôle

Identity card

Global budget: 1855 k€

Public funding: 842 k€

Public funders: Fonds Unique Interministériel (FUI) – DGCIS/Oséo

Call for projects: FUI (FUI AAP3)

Year start: 2007

Completed project (2011-12)


Accredited by the French competitiveness cluster Lyonbiopôle


Strategic business area: Animal Medicines

Application fields: Infectious diseases

Technological approaches / Keywords: Vector vaccine

Stage of development at the beginning of the project: Basic research

Abstract

  The project proposed a unique partnership for establishing the feasibility of the inactivation and the efficacy of vaccines made from candidate viruses and bacteria and solubilization and folding of recombinant proteins obtained from E.coli inclusion bodies , characterizing the pressurized viruses and increasing the cognition on viruses inactivation by high pressure, and developing a High Pressure Equipment on the basis of the critical parameters identified during the feasibility studies and also taking in account the technical constraints and the pharmaceutical environment.


Objectives

The objective of the project is to define the feasibilty of the inactivation of viruses and bacteries using high pressure and to develop a High Pressure Equipment on the basis of the critical parameters defined during the inital phase of the project.


Innovative assets
Highlights
Actual results
Perspectives

Innovative assets

Inactivation of some viruses and bacteries has been possible in some specific conditions and a High Pressure equipment has been defined to work under pharmaceutical conditions.

En poursuivant votre navigation sur notre site, vous acceptez l'utilisation des cookies et la collecte de vos données et informations personnelles par Lyonbiopôle, dans les finalités de mesurer le trafic sur le site Web, de fournir des statistiques et de vous proposer des contenus adaptés à vos centres d’intérets. Pour exercer vos droits d'accès, de rectification, d'opposition, de suppression et de portabilité, conformément au règlement général sur la protection des données (UE n°2016/679), vous etes informés que vous pouvez envoyer votre demande à dpo@lyonbiopole.com. Plus de détails sont disponibles en cliquant ici J'accepte