Strategic area of application
Human Medicine
Application market
Immune, AutoIm & Inflam. diseases - Neurological diseases - Oncology
Activities
Diagnostics - CRO
Technologies
Analytical & Diagnostic services - Cell Therapy - cell biology - Biobanking - Antibodies - Protein - Peptide
Presentation of company's activity
What do all therapies under development have in common? Whether in preclinical or clinical stage, they all need robust and reliable biomarker monitoring tools to track and characterize their biological effect.
Active Biomarkers is a global leader in immunomonitoring, offering expert biomarker testing services to advance therapies from discovery to clinical stages.
Our offer combines tens of years of clinical experience, the highest quality environment, and the largest panel of immunoassay technologies in Europe.
Our fields of expertise include oncology, infectious diseases, inflammatory, auto-immune, or neurodegenerative conditions. High versatility: large menu of prequalified biomarkers or innovative customized assays.
Using key technologies such as single-plex ELISA, multiplex Luminex or SP-X (Quanterix) immunoassays, ultra-sensitive immunoassays on SiMoA HD-1(Quanterix)or MSD platforms, ELISpot, multi-parametric flow cytometry, other cell-based assays, Active Biomarkers offers multiple fit-for-purpose bioanalytical solutions and supports dozens of clinical trials.
Key features of company
Strong scientific expertise in immunology combined with a robust experience in immunomonitoring technologies
Quality-focused services: regulatory compliant, full traceability and stringent quality controls
Active participation to several proficiency panels (ELISpot, Multimer staining, NK cells, Luminex...).
Active Biomarkers is certified for R&D tax credit (CIR).
Recent news
November 2020: the company (formerly part of ABL Group) has been acquired by its senior management team supported by Turenne Santé Group, one of the largest French investment funds specialized in healthcare industry.
January 2018: ABL scales up its capabilities and starts supporting its first Phase III studies
July 2016: Platine Pharma Services becomes ABL Lyon
July 2014 : ABL Inc. acquires majority interest in Platine Pharma Services
June 2013 : Platine Pharma Services and Indicia Biotechnology join forces to strengthen leadership in immune-assays
December 2011: Indicia Biotechnology acquires the rights to the activity Immuno'line and strengthens its offering in the evaluation of the immunogenicity of biopharmaceuticals.
Skills and know-how
Our expertise include :
- Assay Development and method validation for ELISA, multiplex or ultra-sensitive immuno-assay technologies.
- Flow cytometry and ELISpot assay Development and method qualification
- ADA measurements & characterization,
- Optimal sample preparation through our international PBMC reference lab network (PBMC, Sera, Plasma, ...)
- Sourcing of clinical samples
- Prototyping of Diagnostic tools
Higlights
In November 2020, the company (formerly ABL Immuno) has been acquired by its senior management team supported by Turenne Santé Group, one of the largest French investment funds specialized in healthcare industry.
Presentation of company's services
Immunoassay development on different technology platforms: Quanterix, Singulex, Aushon, Luminex, MSD, ELISA
Method validation
Bioanalysis of clinical samples (up to phase 4 studies).
Functional characterization of immune cell subsets by flow cytometry (cell proliferation, cytotoxicity, cytokine secretion)
Quantification of antigen-specific cellular responses by ELISpot, flow cytometry or multiplex or ultrasensitive immunoassays
Receptor saturation assay by flow cytometry
Immune checkpoint inhibitors and CAR-T cells testing
International PBMC network and sourcing of qualified biological samples
Presentation of company's technologies
Gyrolab Technology: expert immunoassays from Gyros
MSD: Mesoscale Discovery multiplex anlysis system
xMAP (Luminex) : bead based multiplex immunoassays
QUANTERIX Simoa HD-1: automated ultrasensitive immunoassay
SP-X Quanterix sensitive and multiplex immunoassays
VIDAS system for IVD assays
ELISpot
ELISA: colorimetric, fluorimetric & luminescent
FACS CANTO II, Multiparametric flow cytometry (8 colors)
