BCI

The main objective of our research laboratory is to increase our understanding of the molecular mechanismms of infection and cancer. and to develop medical applications of diagnostic or therapeutic interest. In infectiology, our intersts are focused on the type III toxin secretion system and on a newly discovered virulence factor (Exolysine-A) of Pseudomonas aeruginosa and on the host cell-pathogenic bacteria interactions. In cancer research, our efforts are centered on the mechanisms of tumor angiogenesis and tumor dissemination (invasuion, EMT) and on targeted therapies (protein-kinase inhibitors, anti-angiogenic molecules).