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MaaT Pharma Announces First Patient Dosed in Phase 2 Clinical Trial of Lead Product MaaT013

 A First-in-Class Biotherapeutic to Treat Acute GvHD

 

 

Lyon, France, October 12, 2018 – MaaT Pharma announced today the dosing of the first patient in a Phase 2 clinical trial of its lead microbiome restoration candidate, MaaT013, in patients with steroid-resistant acute Graft-versus-Host-Disease (SR-aGvHD), the most deadly complication in patients that have undergone allogenic hematopoietic stem cell transplantation, a potentially curative therapy against many hematological diseases. aGvHD is a leading cause of death following an allogeneic stem cell transplant due to the transplanted immune cells attacking the patient’s tissues.

 

It results in a very dismal outcome and poor overall survival in patients not responding to first line therapy as there are no second-line treatments available. MaaT013 is differentiated by its high microbial diversity and richness that can restore the patient’s functional microbiome with the goal of re-establishing homeostasis.

 

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